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Computers — The Machines We Think With

by D. S. Halacy

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Digital Doctor

Medical electronics is a fairly well-known new field of science, but the part being played in medicine by the computer is surprising to those of us not close to this work. Indicative of the use of the computer by medical scientists is a study of infant death rates being conducted by the American Medical Research Foundation. Under the direction of Dr. Sydney Kane, this research uses a UNIVAC computer and in 1961 had already processed information on 50,000 births in ninety participating hospitals. Punched-card data include the mother’s age, maternal complications, type of delivery, anesthetics used, and other pertinent information. Dr. Kane believes that analysis by the computer of this information may determine causes of deaths, after-birth pathological conditions, and incapacity of babies to reach viability. A reduction in infant mortality of perhaps 12,000 to 14,000 annually is believed possible as a result of the studies.

Another killer of mankind, cancer, is being battled by the computer. Researchers at the University of Philadelphia, supported in part by the American Cancer Society, are programming electronic computers to act as cancer cells! The complexity of the problem is seen in the fact that several man-years of work and 500 hours of computer programming have barely scratched the surface of the problem. A third of a million molecules make up the genes in a human cell, and the actions of these tiny components take place many times faster than even the high-speed computer can operate. Despite the problems, some answers to tough chemical questions about the cancer cells are being found by using the computer, which is of course thousands of times faster than manual computation.

If you were discharged from a hospital in 1962, there is a chance that your records are being analyzed by a computer at Ann Arbor, Michigan as part of the work of the Commission on Professional and Hospital Activity. Information on 2-1/2 million patients from thirty-four states will be processed by a Honeywell 400 computer to evaluate diagnostic and hospital care and to compare the performance of the various institutions.

In the first phase of a computerized medical literature analysis and retrieval system for the National Library of Medicine, the U.S. Public Health Service contracted with General Electric for a system called MEDLARS, MEDical Literature Analysis and Retrieval System. MEDLARS will process several hundred thousand pieces of medical information each year. New York University’s College of Engineering has formed a biomedical computing section to provide computer service for medical researchers. Using an IBM 650 and a Control Data Corporation 1604, the computer section has already done important work, including prediction of coronary diseases in men under forty.

The success of computers in these small-scale applications to the problems of medicine has prompted the urging of a national biomedical computer system. It is estimated that as yet only about 5 per cent of medical research projects are using computer techniques, but that within ten years the figure will jump to between 50 and 75 per cent.

An intriguing possibility is the use of the computer as a diagnostic tool. Small office machines, costing perhaps only $50, have been suggested, not by quacks or science-fiction writers, but by scientists like Vladimir Zworykin of the Rockefeller Institute of Medical Research. Zworykin is the man who fathered the iconoscope and kinescope that made television possible. The simple diagnostic computer he proposes would use information compiled by a large electronic computer which might eventually catalog the symptoms of as many as 10,000 diseases. Using an RCA 501 computer, a pilot project of this technique has already gathered symptoms of 100 hematological diseases.

Another use of the computer is in the HIPO system. Despite its frightening acronymic name, this is merely a plan for the automated dispensing of the right medicine at the right time to the right patient, thus speeding recoveries and preventing the occasional tragic results of wrong dosage. More exotic is a computer called the Heikolator which is designed to substitute for the human brain in transmitting messages to paralyzed limbs that could otherwise not function.

The simulation of body parts by the computer for study is already taking place. Some researchers treat the flow of blood through arteries as similar to the flow of water through a rubber tube, analyze these physical actions, and use them in computer simulation of the human system. The Air Force uses a computer to simulate the physical chemistry of the entire respiratory and circulatory systems, a task that keeps track of no less than fifty-three interdependent variables.

Dr. Kinsey of the Kresge Eye Institute in Detroit is directing computer work concerning the physiology of the eye. According to Kinsey it was impossible previously to approximate the actual composition of cell substances secreted from the blood into the eye. Even those whose eyes no longer serve them are being benefited by computer research. The Battelle Memorial Institute in Columbus, Ohio, uses an IBM computer to develop reading devices for the blind. These complicated readers use a digital computer to convert patterns of printed letters into musical tones. Further sophistication could lead to an output of verbalized words. Interestingly, it is thought that the research will also yield applications of use in banking, postal service, and other commercial fields.

Russia is also aware of the importance of the computer in the medical field. A neurophysiologist reported after a trip to Russia that the Soviet Union is training its brightest medical students in the use of the computer. Such a philosophy is agreed to by medical spokesmen in this country who state that no other field can make better use of the computer’s abilities. Among advanced Russian work with computers in the biomedical field is a study of the effects on human perception of changes in sound and color.

Visionary ideas like those of radio transmitters implanted in patients to beam messages to a central computer for continuous monitoring and diagnosis are beginning to take on the appearance of distinct possibilities. Some are beginning to wonder if after it has learned a good bedside manner, the computer may even ask for a scalpel and a TV series.

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